I remember vividly the first time I saw Google Maps in the browser. I was blow away by how smooth and natural the scrolling and zooming were. It just worked so well. At the time this was something we expected in applications but not on the web. That seems like a lifetime ago and now just about anything you used to do in a dedicated application can be done in a web browser. This includes image manipulation. Companies like pics.io even provide tools for editing raw files in the browser.
The ability to easily access color data from images on the page offers some interesting possibilities to the web designer such as changing the interface color to complement the color of an image in a gallery, or allowing users to adjust images to suit their taste in real time.
I'd love to know what works and doesn't work — feel free to drop a comment or a hit me up on Twitter: @markmeyerphoto if you have questions or suggestions.